Collagen Synthesis Supreme (13.83 oz)

So often the things are offered are driven by what I see my patient’s desire and what they ask for. But I must admit sometimes I am selfish. I think about what I want and create it and then I share it with you because ultimately, I truly believe we both want the same thing. Products that taste good and work. I love these win-win situations! And that is how Collagen Synthesis Supreme was born. I am elated that now we both can drink our mocha latte flavored collagen every day and watch the magic happen while experiencing the benefits. Collagen is known to improve skin elasticity, reduce visible wrinkles and increase blood flow to the skin for that healthy glow. In addition, it will support the integrity of your connective tissue, support your muscle health and recovery from exercise while also increasing protein synthesis and decreased protein degradation. 


Product Description

Collagen is a primary structural component of connective tissue that accounts for as much as 30% of the body’s total protein.[1] It is found in skin, ligaments, tendons, cartilage, tooth dentin, bone, and muscle, and it is also part of the structure of arteries and veins. Collagen protein has a unique amino acid composition with an unusually high content of glycine and proline along with the modified amino acid hydroxyproline, making it ideal for supporting the turnover and renewal of structural proteins.*[2]

Due to the well-established function of collagen’s contribution to the integrity of articular cartilage, supplemental collagen peptides have been studied for their potential benefit to cartilage health. The results of a randomized, double-blind, placebo-controlled study of subjects (N = 30) with osteoarthritis (OA) who were given placebo or 5 g of collagen peptide twice daily for 13 weeks demonstrated that collagen peptides were effective in improving OA symptoms. The researchers hypothesized that the mechanism for this effect is attributed to the role that collagen peptides play in regulating chondrocyte differentiation and stimulating proteoglycan synthesis, resulting in cartilage tissue support.*[2]

Several studies have explored the effects of collagen peptide supplementation on body composition, strength, and muscle health when combined with resistance exercise. In a randomized, double-blind, placebo-controlled study of recreationally active male subjects (N = 57), the test group was supplemented with 15 g of collagen peptides while engaging in a resistance training program. Both groups showed a slight increase in strength, but an increase in fat-free mass was observed in the supplemented group, suggesting an increased effectiveness when combined with physical activity. Muscle fiber biopsies in subjects did not differ between the test or placebo group, leading the researchers to attribute the increase of fat-free mass in the supplemented group with hypertrophy of contractile muscle cells and possibly a higher increase in connective tissue.*[1]

Many of the studies assessing the effect of collagen protein supplementation combined with resistance training have been conducted with male subjects. However, a 12-week randomized, controlled trial in pre-menopausal subjects (N = 77) showed an increase in muscle strength and fat-free mass in women who combined 15 g of collagen peptide supplementation with resistance exercise three-times per

Beta-hydroxy-beta-methylbutyrate (HMB) is a metabolite of the essential amino acid leucine found naturally within human muscle cells, and it has been reported to have anabolic effects on protein muscle metabolism.[4,5] Several mechanisms of action have been proposed to explain the action of HMB on muscle health. Among them are that HMB attenuates training-induced proteolysis via downregulation of proteolytic pathways, and it acts as a signaling molecule for stimulation of protein synthesis.[5-7] Studies conducted mostly in athletes have suggested that HMB supplementation may exert beneficial effects on muscle mass and function, most notably when combined with resistance-type exercise training.*[6,8]

In a randomized, double-blind, placebo-controlled, parallel design study, subjects (N = 31) aged 70 and older were given 3 g of HMB or placebo daily for eight weeks with a prescribed exercise program for five days per week. In the supplemented group, subjects showed an increase in lean body mass similar to that seen in younger adults, which reported a decrease in muscle proteolysis and an increase in fat-free mass in young adults with resistance training. The researchers suggested that the results are indicative of the role HMB plays in decreasing proteolysis.*[9]

Results from a randomized study in young, healthy, sedentary subjects (N = 37) given 3 g of supplemental HMB daily for three weeks showed an increase in fat-free mass and total body strength suggesting that HMB partially attenuates muscle protein breakdown without exercise.[10] To further illustrate the benefit of HMB supplementation on muscle health without any form of exercise, a randomized, double-blind, placebo-controlled, parallel design study was conducted with healthy subjects (N = 24) aged 60-76 years who were confined to complete bed rest. Subjects in the test group were given 3 g of HMB five days prior to bed rest until the end of the 10-day rehabilitation phase, resulting in the preservation of muscle mass when compared to the placebo group. Results suggested that HMB helped to preserve muscle mass during the immobilization period.*[11]


*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.